“Decision with Precision”

News and Publications

FASTBASE SOLUTIONS was granted the phase 1SME Instrument as well as the EU Seal of Excellence

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma Author links open overlay panel
BBA Clinical 8 (2017) 97–102

James Miles, Christopher J. Applebee, Pierre Leboucher, Sonia Lopez-Fernandez, Dae-Jin Lee, Rosa Guarch, Stephen Warde Peter J. Parker, Jose I. López, Banafshé Larijani (2017)

Uncoupling TORC2 from AGC kinases inhibits tumour growth.
Oncotarget August 2017 DOI: 10.18632/oncotarget.20086

Angus J.M. Cameron, Selvaraju Veeriah, Jacqueline J.T. Marshall, Elizabeth R. Murray1, Banafshé Larijani and Peter J. Parker (2017)

Vesicular PtdIns(3,4,5)P3 and Rab7 are key effectors of sea urchin zygote nuclear membrane fusion.
2017. Published by The Company of Biologists Ltd Journal of Cell Science (2017) 130, 444-452 doi:10.1242/jcs.193771

M.G.Lete, R.B.Byrne, A.Alonso, D.Poccia, B.Larijani. (2017)

Functional proteomic biomarkers in cancer
Ann N Y Acad Sci. 1346(1):1-6 doi: 10.1111/nyas.12749

Larijani B, Perani M, Alburai’si K, Parker PJ. (2015)

Conservation of proteo-lipid nuclear membrane fusion machinery during early embryogenesis.
Nucleus 5(5):441-8. doi: 10.4161/nucl.34422.

Byrne RD, Veeriah S, Applebee CJ, Larijani B. (September 2014)

Akt/PKB activation in human primary breast carcinoma is a poor prognostic marker: determined by high throughput coincidence amplified-FRET.
S.Veeriah, P.Leboucher, Naurois, N.Jethwa, E.Nye, T.Bunting, R.Stone, V.Calleja, G.Stamp, S.Jeffrey, P.J.Parker, B.Larijani (2014)
HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.
PLoS One. Aug 6;3 (8):e2881

Kong A, Calleja V, Leboucher P, Harris A, Parker PJ, Larijani B. (2008)

Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer.
Cancer Res. 2006 Mar 1;66(5):2834-43.

Kong A, Leboucher P, Leek R, Calleja V, Winter S, Harris A, Parker PJ, Larijani B. (2006)